KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLTF
All Species:
0.91
Human Site:
Y332
Identified Species:
1.54
UniProt:
Q14527
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14527
NP_003062.2
1009
113929
Y332
K
N
L
L
K
K
E
Y
N
V
N
D
D
S
M
Chimpanzee
Pan troglodytes
XP_001138277
1009
113822
C332
K
N
L
L
K
K
E
C
N
V
N
D
D
S
M
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534300
1106
124184
K429
I
K
K
N
Q
M
K
K
E
C
N
V
N
D
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q6PCN7
1003
113298
N326
L
S
K
R
G
K
K
N
H
P
G
K
E
Y
K
Rat
Rattus norvegicus
NP_001099948
974
110023
G297
G
I
L
A
D
D
M
G
L
G
K
T
L
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508504
884
99044
K287
E
L
S
E
P
P
R
K
I
K
G
N
M
K
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090145
999
112576
L322
K
T
L
S
V
I
A
L
I
L
T
N
F
Y
D
Zebra Danio
Brachydanio rerio
XP_693071
942
104740
P312
P
L
E
K
C
K
G
P
S
M
P
S
A
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
E380
I
D
T
L
D
W
D
E
L
S
E
A
V
N
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786706
1093
121576
S408
T
G
R
P
K
R
A
S
A
A
K
V
K
F
I
Poplar Tree
Populus trichocarpa
XP_002308876
799
88908
L202
N
R
E
N
S
G
E
L
P
P
F
W
E
E
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF61
881
98598
A284
P
L
R
G
G
V
F
A
D
D
M
G
L
G
K
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
H193
P
F
Q
L
E
G
L
H
W
L
I
S
Q
E
E
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
E490
D
F
S
T
P
E
A
E
P
A
N
T
F
A
M
Conservation
Percent
Protein Identity:
100
99.5
N.A.
85.5
N.A.
83.6
81.4
N.A.
71.7
N.A.
64.3
53.1
N.A.
21.1
N.A.
N.A.
34.5
Protein Similarity:
100
99.8
N.A.
88
N.A.
89.7
87.9
N.A.
78.5
N.A.
79.3
69.8
N.A.
41.2
N.A.
N.A.
53.1
P-Site Identity:
100
93.3
N.A.
6.6
N.A.
6.6
6.6
N.A.
0
N.A.
13.3
6.6
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
N.A.
26.6
N.A.
33.3
13.3
N.A.
13.3
N.A.
26.6
20
N.A.
26.6
N.A.
N.A.
20
Percent
Protein Identity:
33.6
N.A.
N.A.
36
22.7
25.2
Protein Similarity:
50.4
N.A.
N.A.
52.7
40.9
43.9
P-Site Identity:
6.6
N.A.
N.A.
0
6.6
13.3
P-Site Similarity:
13.3
N.A.
N.A.
6.6
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
22
8
8
15
0
8
8
8
8
% A
% Cys:
0
0
0
0
8
0
0
8
0
8
0
0
0
0
0
% C
% Asp:
8
8
0
0
15
8
8
0
8
8
0
15
15
8
8
% D
% Glu:
8
0
15
8
8
8
22
15
8
0
8
0
15
15
15
% E
% Phe:
0
15
0
0
0
0
8
0
0
0
8
0
15
8
0
% F
% Gly:
8
8
0
8
15
15
8
8
0
8
15
8
0
8
0
% G
% His:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% H
% Ile:
15
8
0
0
0
8
0
0
15
0
8
0
0
0
8
% I
% Lys:
22
8
15
8
22
29
15
15
0
8
15
8
8
15
22
% K
% Leu:
8
22
29
29
0
0
8
15
15
15
0
0
15
0
0
% L
% Met:
0
0
0
0
0
8
8
0
0
8
8
0
8
0
22
% M
% Asn:
8
15
0
15
0
0
0
8
15
0
29
15
8
8
0
% N
% Pro:
22
0
0
8
15
8
0
8
15
15
8
0
0
0
0
% P
% Gln:
0
0
8
0
8
0
0
0
0
0
0
0
8
0
8
% Q
% Arg:
0
8
15
8
0
8
8
0
0
0
0
0
0
0
8
% R
% Ser:
0
8
15
8
8
0
0
8
8
8
0
15
0
15
0
% S
% Thr:
8
8
8
8
0
0
0
0
0
0
8
15
0
8
0
% T
% Val:
0
0
0
0
8
8
0
0
0
15
0
15
8
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
8
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
15
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _